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ARF4 (aa137-150) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P18085 |
| Other Accession | NP_001651.1, 378, 11843 (mouse), 79120 (rat) |
| Reactivity | Human, Mouse |
| Predicted | Rat, Pig |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 20511 Da |
| Gene ID | 378 |
|---|---|
| Other Names | ADP-ribosylation factor 4, ARF4, ARF2 |
| Dilution | WB~~1:1000 E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ARF4 (aa137-150) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ARF4 |
|---|---|
| Synonyms | ARF2 |
| Function | GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Part of the ciliary targeting complex containing Rab11, ASAP1, Rabin8/RAB3IP, RAB11FIP3 and ARF4, which direct preciliary vesicle trafficking to mother centriole and ciliogenesis initiation (PubMed:25673879). |
| Cellular Location | Golgi apparatus. Membrane; Lipid-anchor |
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Provided below are standard protocols that you may find useful for product applications.
References
Regulation of ADP-ribosylation factor 4 expression by small leucine zipper protein and involvement in breast cancer cell migration. Jang SY, Jang SW, Ko J. Cancer Lett. 2012 Jan 28;314(2):185-97. PMID: 22004728
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